#Peep medical abbreviation update#

But it did not seem to predict prognosis to moderate to severe ARDS. Higher DP was significantly associated with an increased risk of death among ventilated patients with ARDS. An exploratory post hoc subgroup analysis and higher DP significantly increased mortality in the mild to severe ARDS subgroup (RR 1.28 95%, 1.14–1.43 I 2 =0), but not in the moderate to severe ARDS subgroup (RR 1.18 95%, 0.95–1.46 I 2 =52%). One of the subgroups investigated, ARDS severity, could account for the heterogeneity. Sensitivity analysis indicated that one study significantly affected the stability of pooled results. Higher DP showed a significant association with higher mortality (pooled risk ratio, 1.10 95%, 1.05–1.16 I 2 =58%).

A total of seven studies comprising 8010 patients were included in this meta-analysis. RevMan 5.3 software was used for all statistical analyses.

Two investigators conducted the literature search study selection, data extraction, and quality evaluation independently. PubMed, the Cochrane Library, ISI Web of Knowledge, and Embase were systematically searched from inception to June 2018.

#Peep medical abbreviation update#

The aim of this study was to systematically and quantitatively update and assess the association between DP and mortality among ventilated patients with ARDS. Driving pressure (DP) has recently become a promising mediator for the identification of the effects of mechanical ventilation on outcomes in acute respiratory distress syndrome (ARDS).